The structural science of dissipative systems

Two operations. Four regimes. A universal pattern that every system follows when it maintains itself by spending energy it cannot recover — from stars to cells to organisations.
Φ > 0 — each cycle generates what was not there before
24
Systems mapped
384/384
Positions matched
0.6%
MAE drug predictions
5
SM constants derived
η = (2/π) J²
The baryon asymmetry of the universe — why matter exists — derived from cycle geometry. Published value: 6.10 × 10⁻¹⁰. Predicted: 6.04 × 10⁻¹⁰. No free parameters.
Hiding in plain sight

Consider how science works. A researcher observes something unexpected — a disturbance. She gathers data, reads prior work, forms a preliminary picture. Then she commits to a hypothesis. She builds an experiment, tests it, discards what fails, selects what survives. She publishes — the work encounters the world. Other researchers replicate, challenge, extend. If the finding holds, it becomes established knowledge: maintained, defended, gradually refined.

That sequence — perturbation, construction, encounter, conservation — is the same sequence a star follows from gas cloud to main sequence. The same sequence a cell follows from signal to division. The same sequence a tumour follows from mutation to metastasis. It is the path every dissipative system takes when it maintains itself by spending energy.

The scientific method is itself a dissipative process. The hypothesis lives in the Construction regime — built under constraint, tested, some fail, one is selected. Peer review is Encounter — what was built meets the world. Textbook knowledge is Conservation — maintained by the field until the next perturbation displaces it. The method runs the geometry it was looking for.

Generative Geometry is the structural science underneath the domains. It does not replace physics or biology or ecology. It identifies the geometry that all dissipative processes share — the sequence, the regime transitions, the fractal depth — and derives it from two operations and nothing else. The formula above is the same formula that predicts drug combination response rates in oncology. It is not an analogy. It is one geometry, expressed in different materials.

Physics Chemistry Biology Ecology Geophysics Medicine Organisations stellar evolution nucleosynthesis baryon asymmetry crystallisation nanocrystals protein folding cell cycle immune response embryogenesis forest succession river systems perturbation cycles volcanism water cycle soil formation cancer treatment drug combinations wound healing startups team dynamics paradigm shifts same structure, different materials I II III IV Potentiality Construction Encounter Conservation observation hypothesis publication established knowledge hold: latent · cross: latent hold: active · cross: latent hold: latent · cross: active hold: active · cross: active Generative Geometry Two operations · Four regimes · 16 positions · Fractal depth every dissipative process, the same path
The Cycle
Two operations, four regimes

Every dissipative system is governed by two operations. Hold maintains coherence. Cross enables transformation. Each is either latent or active. The cycle moves through all four combinations in a fixed order — each regime requires the output of the previous one.

Hold
Cross
latent
active
latent
active
I
Potentiality
II
Construction
III
Encounter
IV
Conservation
Potentiality
hold: latent · cross: latent
Everything is possible. Nothing is committed. The system has been disturbed but has not yet chosen a direction. Components gather. A preliminary form is previewed. Then an irreversible threshold is crossed.
Star
A shockwave disturbs a gas cloud. Heavier elements gather. A dense clump forms. Gravity wins — collapse becomes irreversible.
Cell
A growth signal arrives. The cell activates division machinery. A molecular programme previews what is coming. The restriction point — no turning back.
Startup
A founder notices a problem. Co-founders and early ideas gather. A pitch deck previews the future. Incorporation — the company commits.
16 positions, one cycle

Each regime subdivides into four positions through the same two-operation logic. Click any position to see the same step in three different systems.

Position 01
Disturbance
Potentiality
Star
Cell
Startup
Fractal depth: each position contains 4 sub-phases, each sub-phase contains 4 sub-positions. Resolution = 4n. Same geometry, all the way down.
Interactive
Tools

Explore the geometry. Run the calculations. Verify the predictions. Every tool computes from first principles — two operations, integers, and π.

Physics
η = (2/π)J² Explorer
The full derivation chain from two operations to the baryon asymmetry. Five Standard Model constants derived. Fifteen predictions verified. Zero free parameters.
5 constants · 15 predictions · 0 free parameters
Medicine
Drug Combination Response Predictor
Predict drug combination response rates from calibrated structural parameters. Select cancer type, stage, and agents. The formula computes the expected outcome.
82 agents · 7 cancer types · 0.6% MAE
Computational
Generative Geometry Model
The complete computational model in Python. All formulas, all calibrations, all predictions reproducible. Download and run.
Python · Open source · All formulas included
Science
Dissipative System Analyser
Explore the universal sequence. Four regimes, sixteen positions, four generative properties, the force mapping. Every dissipative system follows the same path.
24 systems · 384/384 · 7 domains
Research

All papers published on Zenodo with DOIs. Open access (CC BY-NC 4.0).

η = (2/π)J² — The Baryon Asymmetry and Five Standard Model Constants from Cycle Geometry
2026
Zenodo →
The Geometry of Intervention — A Universal Formula for Intervening in Dissipative Systems
2026
Zenodo →
The Code Truth — A Hypothesis on the Geometric Unification of Fundamental Forces
2026
Zenodo →
There Is Only One Way to Grow — A Universal Sequence in Dissipative Processes
2026
Zenodo →
The First Principles of Change — Definitions
2026
Zenodo →
Quantitative Tests of the Universal Sequence
2026
Zenodo →
Four Ecological Perturbations and the Generative Properties
2026
Zenodo →
Why Cycles Generate — The Fractal Depth Structure
2026
Zenodo →
Background
About

Generative Geometry was developed by Raimo van der Klein over twenty-five years of observing change in teams, organisations, and systems. The pattern was discovered empirically, formalised structurally, and tested quantitatively across seven scientific domains.

Van der Klein is COO of Pacmed (AI-powered hospital capacity management) and co-founder of Layar (world's first mobile AR browser, 40M+ users). The book Riding Change: How Change Moves, and How to Move With It presents the framework for a general audience.

This is an independent research programme. It is not affiliated with any university or institution. The work is published open-access and the tools are freely available. The geometry belongs to everyone who studies it.